Does This Chemical Make Me Look Fat? 'Obesogens' Lurk All Around Us

There's more to the obesity epidemic than eating too many hot wings and excess sitting. Certainly, poor food choices, particularly too much sugar and sweeteners, and a lack of exercise are major pieces of the obesity puzzle.

But a landmark 2002 study, published in the Journal of Alternative and Complementary Medicine, found the obesity epidemic paralleled the increase of industrial chemicals in the environment. Now researchers are finding that exposures to certain common endocrine-disrupting chemicals—not just lifestyle choices—could be programming us for weight gain, diabetes, and related problems. "We have to acknowledge the fact that obesity is not just about will power, that it's not just all someone's fault," says developmental biologist Retha Newbold, MS, CT, of the National Institute of Environmental Health Sciences.

Animal studies suggest that exposure to certain substances—found in everything from shampoos and soaps to vinyl flooring and pesticides—during fetal development or early in life can disrupt the normal development of an organism's hormonal system, promoting the development of fat cells and hampering the body's ability to send and receive signals that allow it to operate in good health. This sets the stage for metabolic diseases like diabetes as well as a lifetime of weight problems.

Which is why attention to reducing pre-natal exposure is so important. A new study just published online in the journal Environmental Health Perspectives found suspected obesogens in the bodies of many pregnant women, who can pass them along to their developing fetuses. Young children may also be vulnerable to the effects. "It appears that exposure to certain chemicals during critical windows of fetal and early development could permanently program a person for obesity or diabetes, which may not show up for decades down the line," says Newbold. "We're talking about different modes of action. Chemicals could be interacting with the brain, pancreas, or liver, or the fat cells themselves. The end result is going to be obesity."

Suspected obsoegens come in many different forms—here are some of them.

Pesticides

BPA

Personal-care product ingredients

Vinyl

Nonstick products

PCBs

Soy

Nicotine

Pesticides

Previous studies have found an increased rate of diabetes among farmers and pesticide applicators, but it appears that even the low doses that the general public encounters can mess with our hormones. For instance, organochlorine pesticides, such as DDT (now banned, but its harmful breakdown product is persistent in the environment) have been linked to obesity, along with organophosphate pesticides and carbamates (the popular household insecticide Sevin is a carbamate pesticide).

"Pesticides are designed to interfere with a lot of hormonal processes that insects require to replace themselves," explains world-renowned researcher Theo Colborn, PhD, president of The Endocrine Disruption Exchange. "The same chemicals that affect insects affect us."

How to avoid exposure:

Eat organic! Researchers have found that it takes just five days of eating organic to rid the body of virtually all pesticide residues. If the obesity link isn't compelling enough to go organic, consider that other pesticides have been linked to certain cancers, ADHD, autism, Parkinson's disease, and other health issues. And instead of using foggers and insecticide to combat household bug issues, adopt natural pest-control measures in your home.


Bisphenol A (BPA)

Studies in the lab find that BPA has the ability to accelerate fat-cell differentiation, disrupt pancreatic functioning, and cause insulin resistance, leading to obesity problems. In addition, other studies have linked BPA exposure to neurological development problems and sexual reproductive problems, including male infertility, in humans.

How to avoid exposure:

Scientists still don't know the number one exposure source of BPA, but because the chemical is produced in such high volumes, it's been found virtually everywhere. Until more data is collected about how BPA gets into our bodies, one prudent step to take is to minimize your handling of cash-register receipts—some have a high BPA content—so tell cashiers you don't need a receipt for minor purchases. Also, choose food that's fresh, frozen, or sold in glass jars over canned food, since most metal cans contain varying levels of BPA.

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